World commits to a pandemic-response pact: what's next –

Share Article

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.
You can also search for this author in PubMed  Google Scholar
You have full access to this article via your institution.

Attendees of a special session of the World Health Assembly (virtual participants at the European Council shown here) decided to move forward with a new global accord on pandemic preparedness.Credit: François Walschaerts/AFP via Getty
As researchers scrambled this week to learn more about Omicron, the latest SARS-CoV-2 coronavirus variant of concern, world leaders met to negotiate a way of ensuring that a crisis on the scale of the COVID-19 pandemic won’t happen again. Initially on the table was a legally binding pandemic treaty that would dictate how nations should respond to future outbreaks. A fuzzier form of that proposal is now moving forward, to be sharpened in the months and years to come.
“Omicron demonstrates just why the world needs a new accord on pandemics,” said Tedros Adhanom Ghebreyesus, director-general of the World Health Organization (WHO), at the start of the special session of the World Health Assembly, which was held from 29 November to 1 December in Geneva, Switzerland. At the close of the meeting, he cited the need for a contract to unite countries, saying that it could curtail the “‘me-first’ approaches that stymie the global solidarity needed to deal with a global threat”.

How the world failed to curb COVID
International accords — or other frameworks similar to a treaty — typically take years to become reality, and the process for this one is expected to continue until at least 2024. The pivotal decision to move forward with a ‘new instrument’ — made by the WHO’s 194 member states — is only the first step. This decision stems from more than 200 recommendations made by 5 committees of researchers and policymakers who have dissected what has gone wrong during the COVID-19 pandemic.
“The failures have been colossal and systemic — we are living in a broken world,” says Stephen Morrison, director of global health policy at the Center for Strategic and International Studies in Washington DC. “What better a time to try to get something going that addresses the fundamental problems?”
Here, Nature explains the negotiations and the prospects for revamping global cooperation.
After considering a wide range of recommendations for improving the global pandemic response, attendees from the WHO’s member states decided to take several actions. One is to strengthen the WHO’s International Health Regulations (IHRs) — a set of international laws designed to slow the spread of a disease. One change that could be discussed next year is granting the WHO the ability to declare a pandemic (currently, it can only declare a ‘public health emergency of international concern’ — a move that didn’t elicit a strong global response for COVID-19).
European Council President Charles Michel pushed for a pandemic treaty to improve the world’s response to outbreaks.Credit: François Walschaerts/AFP via Getty
But the biggest decision made by the assembly is to collectively develop an accord, agreement or other ‘instrument’ to govern the global pandemic response, including ensuring the equitable distribution of diagnostic tests, drugs and vaccines. A measure in addition to the IHRs is helpful, experts say, because those regulations do not oversee vaccines or other means of fighting pathogens.
The original proposal for such an instrument, driven largely by the president of the European Council, Charles Michel, contained strong terms such as ‘legally binding’ and ‘treaty’, but these were notably absent from today’s announcement. Treaties tend to be legally binding, meaning that a country that doesn’t comply might be taken to international court.
Many presidents and prime ministers ignored WHO recommendations regarding the COVID-19 pandemic and have not been held accountable for their actions, according to several analyses. For this reason, the European Council and Tedros, along with representatives of a number of countries, including Germany, France and South Africa, have expressed their strong support for a legally binding pandemic treaty. But putting it — or another measure that holds countries accountable — in place would require adoption by two-thirds of the WHO’s 194 member states. Countries that are particularly defensive about their sovereignty, including the United States and China, often oppose treaties. They tend to prefer terms such as ‘accord’, which can be interpreted in various ways. “If you’re more strict, you might get less buy-in,” explains Alexandra Phelan, a global health lawyer at Georgetown University in Washington DC.

The world must learn from COVID before diving into a pandemic treaty
Indeed, backing off of the more rigid terminology of a treaty seems to have drastically increased the number of countries willing to consider the proposal, with all 194 member states reaching a final consensus to move forward. In a statement , the head of the US Department of Health and Human Services, Xavier Becerra, said the United States wished to help shape a “new international instrument”. Becerra might have been influenced by the distressing reports of Omicron. “This past week’s news of a new variant of concern has heightened our antennae,” he said.
Kelley Lee, a global health policy researcher at Simon Fraser University in Burnaby, Canada, says that the future of this proposal will depend on its details, including which aspects of it are legally binding and how it is enforced. Wealthy countries are often eager to require nations to collect and openly report data, such as information on cases and genomic sequences from pathogens, she says. “There is a long-standing perception among many high-income countries that pandemics start ‘out there’, so they focus on early warnings,” she explains. However, the same countries might also push back on the enforcement of rules governing equitable access to vaccines and treatments because, as home to many pharmaceutical companies, they typically act to protect patent rights for economic self-interest, Lee says.
The European Council’s Michel has said that a treaty would be a prime way to ensure the equitable distribution of vaccines and other medical countermeasures, such as protective equipment and diagnostic tests. Some researchers are scratching their heads about how a treaty, agreement or accord will accomplish this goal, in part because of the European Union’s opposition to waiving intellectual-property rights for COVID-19 vaccines — a proposal made by South Africa and India that has stalled because of a lack of consensus. A communications officer at the European Council says that a treaty would not be expected to focus on patent waivers, and that “equitable access can be assured in many ways”.

Why did the world’s pandemic warning system fail when COVID hit?
One way to coax wealthy countries to share goods might be to link the action with sharing data, says Suerie Moon, a global health researcher at the Graduate Institute of International and Development Studies in Geneva. She and others point to the Pandemic Influenza Preparedness (PIP) Framework, created in 2011, as a model. This agreement arose in response to Indonesia withholding influenza samples after being denied access to flu vaccines that were developed on the basis of such samples. Under PIP, countries agreed to share influenza samples so that pharmaceutical companies can make diagnostics, drugs and vaccines. In return, companies agreed to give a portion of those products to the WHO so that it can distribute them equitably.
“With this type of deal, everybody gains something,” Moon says, but she adds that the negotiations are complicated because they involve multiple parties, including governments and pharmaceutical companies. Still, she says, it’s worth trying. “This is the kind of issue that has gone unresolved at the global level, and it must be [resolved] — to end this pandemic and prepare for the next one.”
Revisions to the IHRs will probably be debated at the World Health Assembly meeting next May, and amendments might even be adopted by the end of next year. But a pandemic accord or other such tool will take at least another three years. At the end of the special session today, the WHO announced that an international group of health officials will now start hashing out the details. By 1 August 2022, this group will have a draft of its proposal, including a term to describe what precisely the pact will be.
Health officials will then negotiate the terms for another year, and present the instrument for adoption at the World Health Assembly in May 2024. Countries that are unlikely to ratify a treaty, such as the United States, might still abide by it — if a treaty is the outcome, Phelan says. Like many onlookers, she hopes that the complexity of the issues and the plodding nature of the process do not stall action. “As someone looking at the future and dying to make a change, this has to be a pivotal moment,” she notes.
News Explainer
University of Portsmouth
Portsmouth, United Kingdom
Institute of Cancer Research (ICR)
London, United Kingdom
Medicines and Healthcare Products Regulatory Agency (MHRA)
London, United Kingdom
Leibniz Institute for Natural Product Research and Infection Biology – Hans-Knöll-Institute (HKI)
Jena, Germany
You have full access to this article via your institution.

An essential round-up of science news, opinion and analysis, delivered to your inbox every weekday.
Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.
Advanced search
Nature (Nature) ISSN 1476-4687 (online) ISSN 0028-0836 (print)
© 2021 Springer Nature Limited


You might also like

Surviving 2nd wave of corona

Surviving The 2nd Wave of Corona

‘This too shall pass away’ this famous Persian adage seems to be defeating us again and again in the case of COVID-19. Despite every effort